4.8 Article

Pd-Catalyzed Intramolecular Oxidative C-H Amination: Synthesis of Carbazoles

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ORGANIC LETTERS
卷 13, 期 14, 页码 3738-3741

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AMER CHEMICAL SOC
DOI: 10.1021/ol201416u

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  1. Ministry of Education, Science and Technology (MEST) [R01-2009-008-3940, 2010-0017149, 2010-0007737]

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A Pd-catalyzed oxidative C-H amination of N-Ts-2-arylanilines under ambient temperature using Ozone as an inexpensive, safe, and easy-to-handle oxidant has been developed. This process represents a green and practical method for the facile construction of carbazoles with a broad substrate scope and wide functional group tolerance.

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