期刊
ORGANIC LETTERS
卷 13, 期 16, 页码 4196-4199出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol201457y
关键词
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资金
- National Natural Science Foundation of China [21072081]
- Fundamental Research Funds for the Central Universities [lzujbky-2009-81]
A palladium-/copper-catalyzed intermolecular C-H amination reaction of indoles has been developed. This reaction proceeds in good to excellent yields to produce a variety of 2-amino-substituted indoles and exhibits excellent regioselectivity at room temperature. Furthermore, chloroamination of indoles provides a simple method for the construction of C-N and C-Cl bonds in one step.
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