期刊
ORGANIC LETTERS
卷 13, 期 10, 页码 2516-2519出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol200234r
关键词
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资金
- national S & T major project [2009ZX09301-001]
- national marine 863 project [2007AA09Z447, 2007AA09Z402]
- NSFC [40976048, 30730108, 20721003, 20772136]
- CAS [KSX2-YW-R-18, SIMM0907KF-09]
- PRIN-MIUR
Two indole alkaloids, phidianidines A (1) and B (2), exhibiting an uncommon 1,2,4-oxadiazole ring linked to the indole system, have been isolated from the marine opisthobranch mollusk Phidiana militaris. The structures of the two metabolites have been elucidated by spectroscopic techniques. Phidianidines exhibit high cytotoxicity against tumor and nontumor mammalian cell lines in in vitro assays.
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