4.8 Article

Recognition Properties of Acyclic Glycoluril Oligomers

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ORGANIC LETTERS
卷 13, 期 15, 页码 4112-4115

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AMER CHEMICAL SOC
DOI: 10.1021/ol201636q

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  1. National Science Foundation [CHE-0615049, CHE-1110911]
  2. Department of Education [P200A090105]

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The fragmentation reaction of bis-nor-seco-CB[10] with 3,5-dimethylphenol (3) delivers methylene bridged glycoluril pentamer 5 in 81% yield. The host-guest recognition properties of the previously known tetramer 4 and those of pentamer 5 and hexamer 6 toward cationic guests in water are used to delineate some Important features of the binding of acyclic CB[n]-type receptors.

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