期刊
ORGANIC LETTERS
卷 13, 期 14, 页码 3556-3559出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol2009208
关键词
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资金
- National Natural Science Foundation [20802078, 20972160, 20772035]
- National Basic Research Program of China [2009CB940900]
- Shanghai University [DF2009-02]
- Pujiang Talent Plan Project [09PJ1409200]
- National Major Scientific and Technological Program for Drug Discovery [2009ZX-09103-101]
Several ligands were designed to promote transition-metal-free cross-coupling reactions of aryl halides with benzene derivatives. Among the systems probed, quinoline-1-amino-2-carboxylic acid was found to serve as an excellent catalyst for cross-coupling between aryl halides and unactivated benzene. Reactions using this inexpensive catalytic system displayed a high functional group tolerance as well as excellent chemoselectivities.
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