期刊
ORGANIC LETTERS
卷 13, 期 12, 页码 3086-3089出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol200987c
关键词
-
资金
- National Institutes of General Medical Sciences [NIGMS P50 GM086145-01]
- National Cancer Institute [R01 CA126827]
- Amgen
- GlaxoSmithKline
- AstraZeneca
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University
A Bronsted acid-catalyzed Prins-type cyclization sequence to construct spirooxindole pyrans in high yields and excellent diastereoselectivity has been developed. The combination of a beta-hydroxy dioxinone fragment and isatin dimethyl acetal generate oxa-spirooxindoles efficiently. These compounds are diversifiable scaffolds that tap into the rich chemistry of dioxinones.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据