期刊
ORGANIC LETTERS
卷 13, 期 11, 页码 2920-2923出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol200971z
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资金
- Netherlands Organization for Scientific Research (NWO)
A method to ribosylate adenosine on the 2' hydroxyl function in an alpha-selective fashion and in good yield is presented. Protective groups chosen for the acceptor and donor used in this glycosylation not only direct alpha-selectivity but also allow the construction of a fully orthogonally protected building block for the future assembly of oligo-ADP-ribosylated peptides and proteins.
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