期刊
ORGANIC LETTERS
卷 13, 期 19, 页码 5156-5159出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol202028t
关键词
-
资金
- Engineering and Physical Sciences Research Council (EPSRC)
- GlaxoSmithKline
The synthesis of various 6-substituted-4-hydroxy-2-pyridinones is reported. The functionalized keto-dioxinones were constructed via a diethylzinc mediated crossed Claisen condensation reaction and subsequent enamine formation, thermolysis, and cyclization-aromatization providing the pyridinone unit.
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