期刊
ORGANIC LETTERS
卷 12, 期 9, 页码 1944-1947出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol1003302
关键词
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资金
- ETH [0-20449-07]
- Roche Research Foundation
Straightforward access toward previously unreported substituted, heterocyclic spiro[3.3]heptanes is disclosed. These spirocyclic systems may be considered as alternatives to 1,3-heteroatom-substituted cyclohexanes, which are otherwise insufficiently stable to allow their use in drug discovery. Conformational details are discussed on the basis of X-ray crystallographic structures.
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