期刊
ORGANIC LETTERS
卷 12, 期 17, 页码 3863-3865出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol101538x
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资金
- National Natural Science Foundation of China [30772652, 90813026]
- National key Tech project for Major Creation of New Drugs [2009ZX09501-010]
A domino synthesis of pyrrolo[1,2-alpha]pyrazine from 1H-2-pyrrolecarbaldehyde and readily synthesized vinyl azides was developed. This reaction proceeded under relatively mild conditions in the presence of base. Additionally, a possible mechanism for the entire sequence is proposed.
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