期刊
ORGANIC LETTERS
卷 12, 期 16, 页码 3618-3621出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol101345z
关键词
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资金
- Cambridge European Trust
- Ralph Raphael Studentship
- Novartis
- BP [1702]
- Royal Society
An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and carboxylic acids using permanganate as the oxidant within a continuous flow reactor is reported. Notably, the generation and downstream processing of MnO2 slurries was not found to cause any blocking of the reactor when ultrasound pulses were applied to the flow system.
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