期刊
ORGANIC LETTERS
卷 12, 期 21, 页码 4732-4735出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol102062t
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-
资金
- National Sciences and Engineering Research Council of Canada
- Egyptian Academy of Scientific Research and Technology
A new synthesis of 2-alkoxy-1,1-cyclobutane diesters and their first use in dipolar cycloadditions is reported. Both the formation of the donor-acceptor cyclobutanes and their subsequent annulation with in situ formed imines are catalyzed by Yb(OTf)(3). Cyclobutanes with carbon donor groups give piperidines with high trans stereoselectivity.
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