C3-Symmetric Chiral Trisimidazoline: Design and Application to Organocatalyst

C-3-symmetric chiral trisimidazoline was designed and synthesized as a new entry of organocatalyst with the concept of constructing C-3-symmetric molecules with three C-2-symmetric chiral components, and the application of this novel catalyst to asymmetric conjugate addition of beta-ketoesters to nitroolefins was described.