期刊
ORGANIC LETTERS
卷 12, 期 24, 页码 5674-5676出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol102491n
关键词
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资金
- American Heart Association [0930120N]
- NSF [0844931]
- NIH [R01GM088226]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0844931] Funding Source: National Science Foundation
Protein S-nitrosation is an important post-translational modification. However, the detection of S-nitrosation is still problematic because S-nitrosation products, that is, S-nitrosothiols, are unstable species. Here a new reaction which can selectively convert unstable S-nitrosothiols to stable thioethers in one-pot under very mild conditions is reported. This reaction has the potential to be applied in the detection of protein S-nitrosation.
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