期刊
ORGANIC LETTERS
卷 12, 期 23, 页码 5414-5417出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol102209p
关键词
-
资金
- Danish Council
- Natural Sciences, Technology and Production Sciences
- Lundbeck Foundation
- Technical University of Denmark
A broadly useful acid-labile traceless azido linker for the solid-phase synthesis of NH-1,2,3-triazoles is presented. A variety of alkynes were efficiently immobilized on a range of polymeric supports by Cu(I)-mediated azide-alkyne cycloadditions. Supported triazoles showed excellent compatibility with subsequent peptide chemistry. Release of pure material (typically >95%) from the solid support was readily achieved by treatment with aqueous TFA.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据