期刊
ORGANIC LETTERS
卷 12, 期 15, 页码 3536-3539出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol1014015
关键词
-
资金
- Israel Science Foundation [037/02]
A novel thiazole-containing cyclic peptide, aeruginazole A (1), was isolated from the cyanobacterium Microcystis sp. strain (IL-323), which was collected from a water reservoir near Kfar-Yehoshua, Valley of Armageddon, Israel. The planar structure of aeruginazole A was established using homonuclear and inverse-heteronuclear 2D NMR techniques, as well as high-resolution mass spectrometry. The absolute configuration of the asymmetric centers was determined using Marfey's method. Aeruginazole A potently inhibited Bacillus subtilis.
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