4.8 Article

Highly Regioselective Palladium-Catalyzed Oxidative Coupling of Indolizines and Vinylarenes via C-H Bond Cleavage

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ORGANIC LETTERS
卷 11, 期 24, 页码 5606-5609

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AMER CHEMICAL SOC
DOI: 10.1021/ol902315w

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  1. Natural Science Foundation of China [20872126]
  2. Zhejiang Provincial Natural Science Foundation of China [R407106]

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A highly regioselective oxidative coupling reaction between indolizines and vinylarenes has been accomplished in the presence of palladium catalysts to give only the branched a-product in high efficiency. The regioselectivity is promoted significantly by bidentate nitrogen ligands.

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