期刊
ORGANIC LETTERS
卷 11, 期 15, 页码 3458-3461出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol901383j
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资金
- University of California
An efficient method to access the fused indoline ring system present in a multitude of bioactive molecules has been developed. The strategy involves the condensation of hydrazines with latent aldehydes to ultimately deliver indoline-containing products by way of an interrupted Fischer indolization sequence. Our studies show that the approach will likely be amenable to the synthesis of complex targets, such as the communesin natural products.
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