期刊
ORGANIC LETTERS
卷 11, 期 22, 页码 5262-5265出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol902197z
关键词
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资金
- National Natural Science Foundation of China [30470196, 30670219]
- Project of Chinese National Programs for High Technology Research and Development [2007AA091502]
Two novel cyclic hexapeptides containing both anthranilic acid and dehydroamino acid units, sclerotides A (1) and B (2), were isolated from the marine-derived halotolerant Aspergillus sclerotiorum PT06-1 in a nutrient-limited hypersaline medium. Both 1 and 2 are photointerconvertible and could be interconverted via a radical reaction Initiated by direct photoisomerization. Both compounds showed moderate antifungal activity. Compound 2 also showed weak cytotoxicity and antibacterial activity.
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