期刊
ORGANIC LETTERS
卷 11, 期 19, 页码 4294-4297出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol901392p
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资金
- NNSF of China [20673132, 60778033]
- Council of the Hong Kong SAR [CityU 123607]
- 863 Program [2009AA03Z318]
- National Basic Research Program of China [2006CB933000, 2007CB936001]
A new quinine derivative PQ, bearing pyrenyl as a fluorophore, was prepared to recognize heparin in aqueous solution. PQ exhibits good selectivity and sensitivity for heparin over other biological molecules. Upon binding with heparin, PQ shows a typical excimer emission peaked at 489 nm along with a weak monomer emission at 376 nm. Moreover, PQ also shows good performance to detect the heparin In serum.
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