期刊
ORGANIC LETTERS
卷 11, 期 8, 页码 1773-1775出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol900295u
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-
资金
- National Institutes of Health (NIH) [GM-46059]
- NIH [GM-F32-75685]
Simple, efficient procedures for the monoarylation of acetate esters and aryl methyl ketones using aryl chlorides are presented. Previously, no general method was available to ensure the highly selective monoarylation of these classes of substrates using aryl chlorides. Using palladium precatalysts recently reported by our group, these reactions are easily accomplished under mild conditions that tolerate a wide array of heterocyclic substrates.
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