期刊
ORGANIC LETTERS
卷 11, 期 20, 页码 4608-4611出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol901875z
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资金
- Centre National de la Recherche Scientifique
- Institut Curie
- INCa
- Ministere de l'Enseignement Superieur et de la Recherche
A convenient one-pot synthesis of 2-aroylindoles using a domino palladium-catalyzed C,N-coupling/carbonylation/C,C-coupling sequence Is described. The reaction involved easily prepared 2-gem-dibromovinylanilines and boronic acids under carbon monoxide. Optimized reaction conditions allowed the construction of a wide variety of highly functionalized 2-aroyl-/heteroaroylindoles in satisfactory yields.
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