期刊
ORGANIC LETTERS
卷 11, 期 14, 页码 3024-3027出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol901040d
关键词
-
资金
- Scientific Research Foundation for the State Education Ministry [107108]
A novel and efficient way of synthesizing 4,5-disubstituted-1,2,3-(NH)-triazoles through palladium-catalyzed and ultrasonic promoted Sonogashira coupling/1,3-dipolar cycloaddition of acid chlorides, terminal acetylenes, and sodium azide in one pot is developed. The reaction scope is quite general, and the methodology can produce excellent yields. The regioselective 1,4,5-trisubstituted-1,2,3-(NH)-triazoles can be made easily from 4,5-disubstituted-1,2,3-(NH)-triazoles.
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