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卷 11, 期 6, 页码 1381-1383出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol900198r
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A multicatalytic synthesis of complex tetrahydrofurans has been developed involving a Bi(OTf)(3)-Catalyzed nucleophilic addition/hydroalkoxylation sequence. Complex tetrahydrofuranyl products may be formed rapidly in high yield and with good diastereoselectivity. The demonstrated scope of hydroalkoxylation has also been expanded to include substrates bearing useful functional handles including carboxylate ester, olefin, nitrile, and nitro groups.
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