期刊
ORGANIC LETTERS
卷 11, 期 2, 页码 489-492出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol802710u
关键词
-
资金
- National Institute of General Medical Sciences [GM60567]
A total synthesis of brevetoxin A is reported. Two tetracyclic coupling partners, prepared from previously reported advanced fragments, were effectively united via a Horner-Wittig olefination. The resulting octacycle was progressed to substrates that were explored for reductive etherification, the success of which led to a penultimate tetraol intermediate. The tetraol was converted to the natural product through an expeditious selective oxidative process followed by methylenation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据