期刊
ORGANIC LETTERS
卷 11, 期 24, 页码 5590-5593出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol902223m
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资金
- Ministry of Land, Transport and Maritime Affairs of Korea
- Brain Korea 21 (BK21) Project
- Ministry of Education & Human Resources Development, Republic of Korea
- National Research Foundation of Korea [핵06A3203] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Three new sesterterpenoids, phorbaketals A (1), B (2), and C (3) which,have a spiroketal of the hydrobenzopyran moiety, were isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral and chemical methods, They exhibited moderate cytotoxicity against human colorectal, hepatoma, and lung cancer cell lines. Furthermore, the cultivation of the bacterial fraction from the sponge afforded compound 1.
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