期刊
ORGANIC LETTERS
卷 10, 期 20, 页码 4457-4460出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol801607r
关键词
-
资金
- Ministerio de Educacion y Cultura [CTQ2007-61132]
An efficient and general synthesis of aziridines by the reaction of imines derived from p-toluenesulfonamides with in situ generated iodomethyllithium, with a simple and rapid experimental protocol, is reported for the first time. The reaction with the chiral aldimine derived from phenylalaninal allowed access to (2R,1'S)-2-(1'-aminoalkyl)aziridine with very high diastereoselectivity, in enantiopure form. A mechanism to explain this novel reaction is proposed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据