期刊
ORGANIC LETTERS
卷 10, 期 21, 页码 4759-4762出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol801757r
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资金
- UPV/EHU-GV/EJ [IT-324-07]
- Spanish MEC [CTQ2007-67528, CSD 2007-00006]
- European Social Fund
The reaction between homophthalic anhydride and imines in the presence of Ticl(4) and diisopropyl ethyl amine is trans-selective. Under these conditions, the reaction using homochiral imines can be highly diastereoselective, thus allowing the synthesis of enantiopure 1,2,3,4-tetrahydro-1-oxoquinoline-4-carboxylic acids.
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