Fluorescent sensing of IP3 with a trifurcate Zn(II)-containing chemosensing ensemble system

A trifurcate receptor containing Zn(II)-dipicolylamine ligands is developed for the fluorescent sensing of IP3, myo-inositol 1,4,5-tris(phosphate), through an indicator displacement approach. The chemosensing ensemble containing the Zn(II) complex and eosin Y as indicator shows the maximum fluorescence restoration for IP3 among various other anions including phosphate derivatives in water buffered at pH = 7.