期刊
ORGANIC LETTERS
卷 10, 期 20, 页码 4593-4596出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol801883f
关键词
-
资金
- National Science Foundation [CHE-0518406]
The 2-hydroxy-5-nitrobenzyl group is shown to be an effective protecting group for diazenlumdiolates. O-2-(2-Hydroxy-5-nitrobenzyl)-substituted diazeniumdiolates display enhanced thermal stability, but efficiently release nitric oxide (NO) in pH 7.4 aqueous solutions. A lipophilic analogue incorporated into hydrophobic polymers shows NO surface flux rates comparable to that of the natural endothelium. Importantly, these polymer formulations also show significantly enhanced biocompatibility in vivo with use of a porcine implant model.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据