期刊
ORGANIC LETTERS
卷 10, 期 21, 页码 5087-5090出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol802104z
关键词
-
资金
- Ministere de l'Education Nationale et de la Recherche
- Centre National de]a Recherche Scientifique
- ICSN
- University Montpellier I [BQR-2008]
We report a simple and highly stereocontrolled strategy toward the total synthesis of isoprostanes based on a bicyclic alpha,beta-epoxy ketone intermediate 6. Bicyclo[3.3.0]octene scaffold permitted stereodirection of reagents allowing stereoselective epoxidation, diastereoselective ketone reduction, and regioselective epoxide opening otherwise not accessible with a simple cyclopentene framework.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据