4.8 Article

Cylindradines A and B: Novel Bromopyrrole Alkaloids from the Marine Sponge Axinella cylindratus

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ORGANIC LETTERS
卷 10, 期 23, 页码 5465-5468

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AMER CHEMICAL SOC
DOI: 10.1021/ol802263j

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  1. Nippon Suisan Kaisha, Ltd
  2. Ministry of Education, Science, Sports, and Culture, Japan

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The novel alkaloids cylindradines A and B were isolated from Axinella cylindratus, and their structures were elucidated by spectroscopic analyses. Stereochemistries of these compounds were determined by X-ray analysis. Cylindradines showed moderate inhibitory activity against the murine leukemia cell line P388.

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