[(CyPF-tBu)PdCl2]:: An air-stable, one-component, highly efficient catalyst for amination of heteroaryl and aryl halides

An air- and moisture-stable palladium catalyst, [(CyPF-Bu-t)PdCl2] (1), for coupling of heteroaryl chlorides, bromides, and iodides with a variety of primary amines is described. Most of these reactions occurred in high yield with 0.001-0.05 mol % catalyst loading. The reactions tolerated a wide range of functional groups.