期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 12, 期 35, 页码 6816-6819出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob01362j
关键词
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资金
- National Institute of Health [CA142746, AI039246, AI078897]
- Kenneth Rainin Foundation
- Chinese Council Scholarship
- NATIONAL CANCER INSTITUTE [R01CA142746] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [P01AI078897, R01AI039246] Funding Source: NIH RePORTER
An L-rhamnose-based hydrogelator self-assembles to form nanofibrils, which, in contrast to the properties of monomeric L-rhamnose, suppress the antibody response of mice to phycoerythrin (PE), a fluorescent protein antigen. As the first example of the supramolecular assemblies of a saccharide to suppress immunity, this work illustrates a new approach of immunomodulation.
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