4.6 Review

Recent advances in dearomatization of heteroaromatic compounds

期刊

ORGANIC & BIOMOLECULAR CHEMISTRY
卷 12, 期 27, 页码 4807-4815

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob00371c

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资金

  1. National Natural Science Foundation of China [21332009, 21262016]
  2. Specialized Research Fund for the Doctoral Program of Higher Education [20120071110009]
  3. Open Project Program of Key Laboratory of Functional Small Organic Molecules, Ministry of Education, Jiangxi Normal University [KLFS-KF-201201]

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Dearomatization reactions provide the most efficient method for the synthesis of spiro- or fused-ring systems from readily available compounds. This review summarizes the recent developments in dearomatization reactions of indoles, pyridines, quinolines, isoquinolines, and some other heteroaromatic compounds. The applications of these methods in total synthesis of natural products are also briefly introduced.

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