Copper-catalyzed redox-neutral C-H amination with amidoximes

Cul-catalyzed reactions of N-alkylamidoximes afforded dihydroimidazoles via sp(3) C-H amination. On the other hand, the reactions of N-benzoylamidoximes resulted in sp(2) C-H amination to form quinazolinones. The reaction mechanisms could be characterized as a redox-neutral radical pathway including a Cu(I)-Cu(II) redox catalytic cycle.