Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons

Chiral cyclohex-2-enones are important building blocks in synthetic chemistry and the life science industries and much attention has been drawn to the development of efficient and practical methodologies for accessing these enantio-enriched cyclohex-2-enone skeletons. This review describes the impressive progress that has been made in terms of employing new methodologies, suitable reactants as well as more efficient catalyst systems for this important enantioselective transformation. Also, the reaction mechanisms are briefly discussed.