期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 12, 期 22, 页码 3616-3621出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob00200h
关键词
-
资金
- National Key Project for Basic Research [2010CB126100]
- National Natural Science Foundation of China [21132003, 21121002, 21372131]
- Tianjin Natural Science Foundation [11JCZDJC20500]
- Specialized Research Fund for the Doctoral Program of Higher Education [20130031110017]
A new asymmetric total synthesis of a phenanthroindolizidine alkaloid (S)-tylophorine is reported, which features a catalytic asymmetric allylation of aldehydes and an unexpected one-pot DMAP promoted isocyanate formation and Lewis acid catalyzed intramolecular cyclization reaction. In addition, White's direct C-H oxidation catalyst system converting monosubstituted olefins to linear allylic acetates was also employed for late-stage transformation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据