期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 12, 期 6, 页码 919-930出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob41800f
关键词
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资金
- Yeungnam University [213A367018]
Novel and efficient one-pot syntheses of a variety of benzo[c]chromen-6-one derivatives were accomplished using Cs2CO3-promoted reactions between substituted 2-hydroxychalcones and beta-ketoesters. These reactions involved domino Michael addition/intramolecular aldol/oxidative aromatization/lactonization and provided a rapid synthetic route for the production of biologically interesting novel benzo[c]chromen-6-one molecules bearing several different substituents on benzene rings. As an application of this methodology, several synthesized benzo[c]chromen-6-ones were transformed into highly functionalized novel terphenyls.
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