期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 11, 期 13, 页码 2168-2174出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob27297d
关键词
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资金
- Japan Society for the Promotion of Science [24750037, 24350022]
- Grants-in-Aid for Scientific Research [24750037] Funding Source: KAKEN
A multicomponent reaction of isocyanides and C,N-cyclic N'-acyl azomethine imines in the presence of TMSCl and NaN3 leads to tetrazole derivatives. These reactions proceeded cleanly to afford the corresponding 1,5-disubstituted tetrazoles containing a tetrahydroisoquinoline skeleton in high to excellent yields.
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