期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 10, 期 11, 页码 2307-2317出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob07172j
关键词
-
资金
- MIUR
- Fondazione del Monte di Bologna e Ravenna [FC 11/2011]
- Italian Minister for Foreign Affairs
- Fondazione per la Ricerca sulla Fibrosi Cistica, Verona
The reaction of sulfonyl peptides containing L- or D-configured Ser or Thr with bis(succinimidyl) carbonate in the presence of a catalytic amount of a base affords, in solution or in the solid phase, the corresponding peptides with one or two, consecutive or alternate oxazolidin-2-ones (Oxd). The Oxd ring can be regarded to as a pseudo-Pro with an exclusively trans conformation of the preceding peptide bond; homochiral Oxd-containing peptides adopt extended conformations, while the presence of a D-configured Oxd favours folded conformations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据