期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 10, 期 43, 页码 8605-8608出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob26604k
关键词
-
资金
- National Natural Science Foundation of China [21202138]
- Xiangtan University [11QDZ20]
- Hunan Provincial Natural Science Foundation of China [12JJ7002]
A practical Bronsted acid promoted benzylic C-H functionalization of 2-methylazaarenes and nucleophilic addition to aldehydes was developed in good to excellent yields. A six-membered hydrogen-bonding transition state is proposed to be crucial for the reaction. Ready availability of the two starting materials, the use of acetic acid as the catalyst and the facile reaction conditions will guarantee this synthetic method attractive to the synthesis of bioactive pyridine and quinoline derivatives.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据