期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 10, 期 35, 页码 7027-7030出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob26002f
关键词
-
资金
- Chinese National Science Foundation [81072528]
- Chinese NSF [81125021]
- National Science and Technology Major Project on 'Key New Drug Creation and Manufacturing Program', China [2012ZX09103-101-035]
- Shanghai Commission of Science and Technology [10410702600, 10JC1417100, 10dz1910104]
We have developed a practical method to assemble the proposed structure of natural product veraguamide A (1) by first preparing the three key fragments followed by optimization of the macrocyclization site. Although the synthetic product gave similar optical rotation to that reported for natural product, significant differences in the H-1 and C-13 NMR spectra were observed, especially the proton and carbon signals in the two N-MeVal moieties.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据