期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 9, 期 20, 页码 6943-6948出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob05818e
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资金
- CSIR
- DST, New Delhi
The utility of thiourea dioxide as an efficient organocatalyst for the library synthesis of novel heterocyclic compounds via one-pot multicomponent coupling reactions is disclosed. Thiourea dioxide is an inexpensive and readily accessible catalyst, resulting in better product yields as compared to the corresponding thiourea as catalyst. Thiourea dioxide is found to be insoluble in various organic solvents and therefore at the end of the reaction products can be separated by extraction with diethyl ether and the recovered catalyst can be used several times with consistent catalytic activity.
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