期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 9, 期 9, 页码 3349-3358出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob00017a
关键词
-
资金
- National Basic Research Program of China (973) [2010CB833302]
- Fundamental Research Funds for the Central Universities
- National Natural Science Foundation of China [21072206, 20472096, 20902019, 20872162, 20672127, 20821002, 20732008, 20772030, 20702059]
Multifunctional chiral phosphine (phosphine-thiourea type) L2-catalyzed allylic substitutions of MBH adducts 1 with oxazolones 2 produce the corresponding optically active adducts 3 in good to excellent yields and ee's as well as moderate to good de's under mild conditions. The synergistic interaction between hydrogen bond donor site and nucleophilic site has been discussed, indicating that finely tuning the active sites of the multifunctional phosphine organocatalysts is very important.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据