期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 9, 期 11, 页码 4199-4204出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob05252g
关键词
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A series of near-infrared fluorescent probes were designed based on the concept of emission control caused by interdye excitonic interaction. The fluorescent probes showed very weak emission in the unhybridized state, whereas they emitted near-infrared fluorescence after hybridization with the complementary nucleic acid. The hybridization-dependent switching of fluorescence emission made it possible to monitor mRNA in human cells in the range of near-infrared wavelengths.
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