期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 9, 期 5, 页码 1402-1406出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00586j
关键词
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资金
- National Natural Science Foundation of China [20772056, 20932004]
- Nanjing University
An efficient method for the asymmetric synthesis of beta-trifluoromethylated beta-amino ketones via addition of ketone-derivative enolates to trifluoromethylated sulfinylimine has been developed, with good chemical yields and excellent diastereoselectivities. This practical method was also proved to be suitable for large-scale preparation.
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