期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 9, 期 20, 页码 7162-7167出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ob05740e
关键词
-
资金
- University of Florida
- Kenan Foundation
- King Abdulaziz University, Jeddah, Saudi Arabia
An efficient approach for the synthesis of a series of S-acyl peptides containing internal cysteine residues has been developed and the chemical long-range ligation of these S-acyl peptides via 5-, 8-, 11- and 14-membered cyclic transition states has been investigated. Our results include the first examples of successful isopeptide ligations starting from S-acyl peptides containing non-terminal cysteine residues and indicate that the cyclic transition states studied in this present paper are decreasingly favored in the order of their sizes 5 >> 14>11 >> 8.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据