4.6 Article

Facile one-pot synthesis of three different substituted thiazoles from propargylic alcohols

期刊

ORGANIC & BIOMOLECULAR CHEMISTRY
卷 8, 期 14, 页码 3259-3266

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c002093a

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  1. National Natural Science Foundation of China [20772098]
  2. Program for New Century Excellent Talents in Fujian Province University

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Three different substituted thiazoles have been successfully synthesized from readily available propargylic alcohols. Various secondary propargylic alcohols or tertiary propargylic alcohols participated well in the reaction, providing the desired products in good yields. This method provides a flexible and rapid route to substituted thiazoles.

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