期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 8, 期 17, 页码 3847-3850出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0ob00174k
关键词
-
资金
- Natural Science Foundation of China [20902025]
- East China Normal University
The direct alpha-cyanoamination of isatins using TMSCN has been developed, which is carried out in methanol without any catalyst. A new bifunctional cinchona alkaloid-based phosphinamide catalyst 7 could promote the Strecker reaction of isatins derived ketimine with TMSCN in up to 74% ee.
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